the most important factor responsible for mortality in miliary TB. The
varied clinical manifestations, atypical radiographic indings and
dif iculties in establishing TB as the aetiological diagnosis, among
others, are challenges in diagnosis and treatment of miliary TB. The
typical chest radiograph indings may not be evident till late in the
disease. Patients with miliary TB classically present with fever with
evening rise of temperature for several weeks duration, anorexia,
weight loss, weakness and cough. However, fever may be absent and
the patients may present with progressive wasting strongly mimicking
a metastatic carcinoma. Dry cough and dyspnoea are often present.
41. Can pulmonary tuberculosis be misinterpreted as lung cancer at
autopsy?
Yes, I have encountered a case in which the convict presented with
respiratory complaints within 1 week of his entry in the prison and
then after about 5 weeks, he presented with haemoptysis, cough with
expectoration and chest pain. For which he was referred to medical
college and subsequently to RNTCP (Revised national tuberculosis
control program) centre where x-ray and CT scan were also done. He
was diagnosed as having pulmonary tuberculosis and was put on
Category -1 ATT (anti-tubercular treatment). But subsequently he
developed chest complication (pleural effusion) and lung collapse and
expired during treatment.
The post-mortem report mentioned lung indings as “well de ined
tumour mass on apical region placed at central region on right main
bronchus”. Tuberculosis is well known as a diagnostic chameleon and
can resemble carcinoma of lung. The well de ined tumour mass on
apical region of lung without any in iltrative appearance and absence
of metastatic indings in the surrounding, other lung or abdominal
viscera is not consistent with the indings as seen in a patient dying due
to carcinoma lungs. Especially in absence of histo-pathological
diagnosis of the diseased condition of lungs, the post-mortem
diagnosis based upon gross post-mortem indings may be more so a
misinterpretation. The indings in this case were more corroborating
with the clinical/ante-mortem diagnosis of pulmonary tuberculosis.
42. How tuberculosis progresses in a patient suffering from it?
MEDICAL DIMENSION OF FREQUENTLY ENCOUNTERED CASES | 42